Wellcome-MRC Institute of Metabolic Science
Jean Adams
evaluates population interventions in dietary public health
Clemence Blouet
investigates how nutrients are detected by the brain to maintain energy homeostasis in health and disease.
Soren Brage
develops and evaluates different methods for assessing physical activity in epidemiological studies with a view to assessing how activity relates to improving health..
Krishna Chatterjee
investigates disorders of thyroid hormone action and the role of nuclear receptors in human disease.
Anthony Coll
studies the molecular mechanisms controlling food intake and energy expenditure.
Miguel Constancia
looks at the role of epigenetics and imprinted genes in foetal growth and metabolism.
Mark Evans
studies hypoglycaemia and glucose sensing in the brain and improving type 1 diabetes management with new technologies.
Sadaf Farooqi
investigates the molecular and physiological pathways involved in regulating human appetite and body weight
Daniel Fazakerley
interested understanding the molecular details of insulin-stimulated glucose transport, and how this process breaks down in disease.
Paul Fletcher
aims to understand choice, behaviour and variability in susceptibility to internally- and environmentally-driven food consumption.
Nita Forouhi
investigates the role that diet and nutrition plays in the risk of developing diabetes, obesity and obesity-related disorders.
Fiona Gribble
explores how gut hormones are released and their actions on target tissues.
Simon Griffin
investigates prevention, early detection and management of obesity and type 2 diabetes.
Mark Gurnell
focuses on optimising the diagnosis and treatment of disorders of the pituitary and adrenal glands.
Roman Hovorka
is developing closed-loop systems (Artificial Pancreas) that could serve as a ‘bridge’ until a cure in the form of either stem cell therapy or islet transplantation becomes available.
Claudia Langenberg
investigates how genetic and lifestyle factors act together in their influence on type 2 diabetes and related metabolic disorders.
Florian Merkle 
studies the molecular and cellular basis of human disease, in particular obesity associated with the aberrant function of specific neuron types in the hypothalamus
David Ogilvie
investigates the effects of interventions to influence the wider environmental or societal determinants of active living and associated behavioural and health outcomes.
Ken Ong
investigates how early life factors, such as infant weight gain, diet and pubertal timing lead to later obesity and develops and tests preventative strategies.
Tolullah Oni
leads the MRC Epidemiology Unit’s Global Public Health Research initiatives.
Stephen O’Rahilly
focuses on molecular mechanisms in human obesity and insulin resistance, and translating this into improvements in diagnosis and therapy.
Susan Ozanne
studies how poor nutrition and obesity during early life influences long-term risk of developing Type 2 diabetes, obesity and cardiovascular disease.
John Perry
focuses on understanding the biological mechanisms that link patterns of early life growth and reproductive ageing to later life cardio-metabolic health.
Polly Page
is responsible for setting up and leading a coordinated platform for the measurement of diet, anthropometry, physical activity and nutritional biomarkers.
Frank Reimann
identifies mechanisms underlying the secretion of peptides with regulatory roles in metabolism.
David Savage
researches the molecular events underpinning human insulin resistance and its contribution to the pathogenesis of Type 2 diabetes.
Nadia Schoenmakers
aims to elucidate the genetic basis of congenital hypothyroidism by identifying and characterising genes causing the disorder.
Kenneth Siddle (Prof Em)
studies the receptors and signalling mechanisms mediating the effects of insulin and IGFs on cellular metabolism and growth.
Esther Van Sluijs
develops and evaluates interventions to promote physical activity in young people, and uses observational research to further understand where, when and how physical activity interventions in young people may be targeted.
Antonio Vidal-Puig
investigates the role of lipotoxicity in the pathogenesis of obesity and the Metabolic Syndrome and on developing novel therapeutic approaches.
Nick Wareham
investigates the association of genes with type 2 diabetes and examines how these associations are modified by environmental factors, such as diet and physical activity.
Martin White
focuses on understanding the determinants of behaviour and the development and evaluation of interventions that impact dietary behaviours.
James Woodcock
works with models to help understand both the health impacts of changes to how we travel and how we eat and to understand how such changes might occur.
Giles Yeo
studies the molecular mechanisms underlying the central control of food intake.
