Our Lead Researchers

BarrosoDr Ines Barroso
studies the genetic bases of common and rare forms of metabolic disease.
BrageDr Soren Brage
develops and evaluates different methods for assessing physical activity in epidemiological studies with a view to assessing how activity relates to improving health.
ChatterjeeProfessor Krishna Chatterjee
investigates the role of nuclear receptors in human disease.
CollDr Tony Coll
studies the molecular mechanisms controlling food intake and energy expenditure.
CollDr Miguel Constancia
looks at the role of epigenetics and imprinted genes in foetal growth and metabolism.
CollProfessor David Dunger
focuses on Type 1 diabetes and its complications, and the developmental origins of Type 2 diabetes.
EkelundDr Ulf Ekelund
investigates how physical activity and sedentary behaviour affects the health of people across their lifespan with particular reference to the development of metabolic disease.
EvansDr Mark Evans
studies glucose-sensing in the brain, and improving Type 1 diabetes management using closed-loop insulin pump systems.
FarooqiProfessor Sadaf Farooqi
investigates the molecular and physiological pathways involved in regulating human appetite and body weight.
ForouhiDr Nita Forouhi
investigates the role that diet and nutrition plays in the risk of developing diabetes, obesity and obesity-related disorders.
GriffinProfessor Simon Griffin
translates knowledge gained from epidemiological studies into action to prevent diabetes, obesity and related metabolic disorders and assesses the effectiveness of different approaches to prevent these conditions and their complications.
HovorkaDr Roman Hovorka
is developing closed-loop systems (Artificial Pancreas) that could serve as a ‘bridge’ until a cure in the form of either stem cell therapy or islet transplantation becomes available.
LangenbergDr Claudia Langenberg
investigates how genetic and lifestyle factors act together in their influence on type 2 diabetes and related metabolic disorders.
MurphyDr Helen Murphy
is working to improve the health outcomes for women and children with Type 1 diabetes.
OgilvieDr David Ogilvie
investigates the effects of interventions to influence the wider environmental or societal determinants of active living and associated behavioural and health outcomes.
OngDr Ken Ong
investigates how early life factors, such as infant weight gain, diet and pubertal timing lead to later obesity and develops and tests preventative strategies.
Professor Sir Steve O'Rahilly
focuses on molecular mechanisms in human obesity and insulin resistance, and translating this into improvements in diagnosis and therapy.
OzanneDr Sue Ozanne
studies how poor nutrition during early life influences long-term risk of developing Type 2 diabetes, obesity and cardiovascular disease.
ReddyDr Ak Reddy
investigates the molecular mechanisms of circadian clocks and how these control aspects of our physiology, including endocrine parameters, metabolism and the sleep-wake cycle.
SavageDr David Savage
researches the molecular events underpinning human insulin resistance and its contri­bution to the pathogenesis of Type 2 diabetes
SempleDr Rob Semple
focuses on the genetic, cellular and molecular basis of human genetic disorders of insulin action, from severe insulin resistance to spontaneous non-insulin-dependent hypoglycaemia.
SiddleProfessor Ken Siddle
studies the receptors and signalling mechanisms mediating the effects of insulin and IGFs on cellular metabolism and growth.
Van SluijsDr Esther Van Sluijs
identifies individual, social and environmental correlates and determinants of young people's physical activity behaviour to inform intervention development and evaluates physical activity promotion interventions.
Vidal-PuigProfessor Toni Vidal-Puig - investigates the role of lipotoxicity in the pathogenesis of obesity and the Metabolic Syndrome and on developing novel therapeutic approaches.
WarehamProfessor Nick Wareham
investigates the association of genes with type 2 diabetes and examines how these associations are modified by environmental factors, such as diet and physical activity.
YeoDr Giles Yeo
studies the molecular mechanisms underlying the central control of food intake.

Working together to translate research into better health